Background Biobank participants often do not understand much of the information they are provided as part of the informed consent process, despite numerous attempts at simplifying consent forms and improving their readability. We report the first assessment of biobank enrollees’ comprehension under an "integrated consent” process, where patients were asked to enroll in a research biobank as part of their normal healthcare experience. A number of healthcare systems have implemented similar integrated consent processes for biobanking, but it is unknown how (...) much patients understand after enrolling under these conditions. Methods: We recruited patients who enrolled in a biobank while in a healthcare setting when receiving ordinary care. We assessed knowledge of consent materials using 11 true/false questions drawn from a well-known biobank knowledge test. After reviewing the results from 114 participants, we revised the consent form and repeated the knowledge assessment with 144 different participants. Results: Participants scored poorly on the knowledge test in both rounds, with no significant differences in overall scores or individual items between the rounds. In Phase 1, participants answered 53% of the questions correctly, 25% incorrectly, and 22% “I don’t know.” In Phase 2, participants answered 53% of questions correctly, 24% incorrectly, and 23% “I don’t know.” Participants scored particularly poorly on questions about data sharing and accessing medical records. Conclusions: Enrollees under an integrated consent model had significant misunderstandings that persisted despite an attempt to improve information specifically about those topics in a consent form. These results raise challenges for current approaches that attribute misunderstanding to overly complex consent forms. They also suggest that the pressures of the clinic may compound other problems with patient understanding of biobank consent. As health systems increasingly blend research and care, they may need to rethink their approach to educating patients about participation in a biobank. (shrink)

Animal welfare involves societal and human values, ethical concerns and moral considerations since it incorporates the belief of what is right or what is wrong in animal treatment and care. This paper aims to ascertain whether the different dimensions of individual attitudes toward animal welfare in food choices may be characterized by general human values, as identified by Schwartz. For this purpose, an EU-wide survey was carried out, covering almost 2500 nationally representative individuals from five European countries. Compared with (...) the previous literature this study shows a twofold novelty: it develops a general framework to link individual enduring beliefs and attitudes toward animal welfare attributes in food choices; the framework is analyzed within a broad-based cross-country study. Our empirical results prove that human values related to self-transcendence are strongly associated to overall animal welfare attitudes and especially to those explicitly related to food choices, while values related to the spheres of self-enhancement and conservatism are significantly associated to less sensitive attitudes to animal welfare. Moreover, our results appear to indicate that a determinant of animal welfarism in food choices is potentially associated to individual concerns regarding food safety issues. (shrink)

This monograph attempts to clarify one significant but much neglected aspect of Peirce's contribution to the philosophy of science. It was written in 1963 as my M. A. thesis at the Uni versity of Illinois. Since the topic is still neglected it is hoped that its pUblication will be of use to Peirce scholars. I should like to acknowledge my indebtedness to Dr. Max Fisch who broached this topic to me and who advised me con tinuously through its development, assisting (...) generously with his own insights and unpublished Peirce manuscripts. TABLE OF CONTENTS INTRODUCTION 1. A Current Issue in the Philosophy of Science 1 2. Peirce and His Theory of Abduction 5 3. The General Character of Abduction 7 PART I: THE EARLY THEORY 1. Peirce's Earliest Conception of Inference 11 2. Three Kinds of Inference and Three Figures of Syllogism 13 3. Ampliative Inference and Cognition 17 4. Induction and Hypothesis 20 5. The Method of Methods 23 PART II: THE LATER THEORY 1. The Transitional Period 28 2. Three Stages of Inquiry 31 3. Abduction and Guessing Instinct 35 4. Logic as a Normative Science 38 5. Hypothesis Construction and Selection 41 6. Abduction and Pragmatism 44 7. Economy of Research 47 8. Justification of Abduction 51 CONCLUSION 55 61 BIBLIOGRAPHY INTRODUCTION 1. (shrink)

On April 3, 1995, the Fourth Circuit upheld the right of a Maryland hospital to terminate a surgeon who was HIV-positive ). A resident in the University of Maryland Neurosurgical Training Program was dismissed when hospital administrators learned of his infection with HIV. The resident, known as Dr. Doe, claimed that his termination violated federal laws protecting persons with disabilities. The court upheld the hospital's actions as lawful and affirmed the trial court's grant of summary judgment for the hospital.Dr. Doe (...) charged that his dismissal from the training program violated the Rehabilitation Act and the Americans with Disabilities Act. (shrink)

There is a unique relationship between Maoist policies and philosophy. This uniqueness is idue, on the one hand, to the pedagogical orientation of the CPC, and to the essential role of the cultural revolution, on the other.

JL Austin exercised in Post-war Oxford an intellectual authority similar to that of Wittgenstein in Cambridge. Although he completed no books of his own and published only seven papers, Austin became through lectures and talks one of the acknowledged leaders in what is called ‘Oxford philosophy’ or ‘ordinary language philosophy’. Few would dispute that among analytic philosophers Austin stands out as a great and original philosophical genius. Three volumes of his writing, published after his death, have become classics in analytical (...) philosophy: _Philosophical Papers_; _Sense and Sensibilia_; and _How to Do Things with Words_. First published in 1979, this book is a collection of critical essays on Austin’s philosophy written by well-known philosophers, many of whom knew Austin personally. A number of essays included were especially written for this volume, but the majority have appeared previously in various journals or books, not all easy to obtain. (shrink)

Meiotic recombination occurs preferentially at certain regions called hot spots and is important for generating genetic diversity and proper segregation of chromosomes during meiosis. Hot spots have been characterized most extensively in yeast, mice and humans. The development of methods based on sperm typing and population genetics has facilitated rapid and high‐resolution mapping of hot spots in mice and humans in recent years. With increasing information becoming available on meiotic recombination in different species, it is now possible to compare several (...) molecular features associated with hot‐spot loci. Further, there have been advances in our knowledge of the factors influencing hot‐spot activity and the role that they play in structuring the genome into haplotype blocks. We review the molecular features associated with hot spots in terms of their properties and mechanisms underlying their function and distribution. A large number of these features seem to be shared among hot spots from different species suggesting common mechanisms for their formation and function. BioEssays 28:45–56, 2006. © 2005 Wiley Periodicals, Inc. (shrink)

The recent revival of Confucianism in the PRC raises questions regarding the legitimacy of cultivating Confucian virtues such as ren, li and xiao in an educational context. This article is based on the assumptions that education is an ideologically laden practice and that moral virtues have the potential of functioning to sustain hegemony and other forms of social control. By focusing on the Xiao Jing, a lesser known Confucian classic, it offers the Confucian account of filial piety a charitable reading (...) which then proceeds to examine the ideological dimension of filial piety. By employing concepts such as naturalisation and the public–private distinction in my analysis, I argue that filial piety should be understood through a critical lens. While the question ‘Is filial piety a virtue?’ cannot be answered in a simple, straightforward manner, the discussion on filial piety presented in this article has the potential to shed light on the relationship between politics and moral education. (shrink)

P. M. S. Hacker's tetralogy on human nature (2007–2021) is a recent contribution to philosophical anthropology. In this work, the expression ‘form of representation’ appears at crucial points of discussion. This paper begins with an exposition and analysis of this notion, followed by a look at how it is utilised in the discussion of knowledge, the mind, and other emotive and moral concepts. It then turns to a comparison of ‘forms of representation’ with two important concepts, namely, analogy and metaphor. (...) To offer an evaluation of ‘forms of representation’ as a critical tool, this paper examines the increasingly common tendency for humans to identify with their brains. (shrink)

Each decade since 1979, the Healthy People initiative establishes the national prevention agenda and provides the foundation for disease prevention and health promotion policies and programs. Law and policy have been included in Healthy People objectives from the start, but not integrated into the overall initiative as well as possible to potentially leverage change to meet Healthy People targets and goals. This article provides background on the Healthy People initiative and its use among various stakeholder groups, describes the work of (...) a project aiming to better integrate law and policy into this initiative, and discusses the development of Healthy People 2030 — the next iteration of health goals for the nation. Lessons from the preliminary stages of developing Healthy People by the HHS Secretary's Advisory Committee on National Health Promotion and Disease Prevention Objectives for 2030 and a Federal Interagency Workgroup will be included. Efforts by the Committee focused on the role of law and policy as determinants of health and valuable resources around health equity are also shared. Finally, the article discusses ways that law and policy can potentially be tools to help meet Healthy People targets and to attain national health goals. (shrink)

The double issue of Synthese devoted to essays on the work of W. V. Quine has been re-issued under hard cover with an additional paper by Grice on "Vacuous Names" and a 13-page bibliography of Quine's writings. With the exception of Berry's "Logic with Platonism" and Jensen's "On The Consistency of a Slight. Modification of Quine's New Foundation," the papers are concerned with the key issues of Word and Object. Quine's responses to each of the contributors are not as helpful (...) as they might be, but are at times quite illuminating. He dispels Stenius's view in "Beginning with Ordinary Things" that Quine holds a Russellian epistemology, for example, and clarifies somewhat his account of ontic commitment in replying to Hintikka's "Behavioral Criteria of Radical Translation." Hintikka argues that "to be is to be a value of a bound variable" presupposes the principle, "to be is to be an object of search." Quine rejects this view, identifying his ontology with the range of the variables as opposed to the class of all things to which a theory is ontically committed. The introduction to chapter two of Word and Object by Harman is quite helpful, suggesting among other things that Quine's use of 'propositional attitude' is a misnomer to be better replaced by 'sentential attitude'. An interesting and provocative paper by Kaplan offers a Fregean alternative to Quine's general mode of handling referentially opaque contexts, allowing "Quantifying In" with the variable ranging over expressions. Interestingly enough, Quine's remarks are rather laudatory and sympathetic. Davidson's "On Saying That" suggests a roughly similar account of oratio obliqua discourse. Føllesdal and Sellars discuss "Quine on Modality" and "Some Problems about Belief." There is a discussion of "Quine's Philosophy of Science" by Smart, tracing a shift from instrumentalism to realism on the part of Quine. Also included are papers by Chomsky, Stroud, and Geach, as well as Strawson's familiar "Singular Terms and Predication." In spite of the imposing price and the uneven quality of the essays, the book is a desirable piece of Quineana.--K. T. (shrink)

The history of contemporary modal logic dates back to the writings of C. S. Lewis in the early part of this century. Since then, a growing body of literature has attested to professional interest in the area, and in a number of related issues in philosophical logic which have received wide attention. The recent development of powerful formal techniques for modal system building, together with an increasing interest in modal logic as a tool for philosophical analysis, have created a need (...) for an up-to-date text to introduce students to this material. Snyder's book attempts to answer this need. Assuming an understanding of elementary propositional logic, Snyder introduces a reductive technique called cancellation for detecting the theorems of a system of logic. This technique, analogous to the construction of Smullyan trees but more compact, is extended to modal and quantified contexts. Cancellation versions of the systems M and Mn of G. H. von Wright, and S4 and S5 of Lewis are developed. Snyder uses a Hintikka type of semantics, showing how the various formal systems are differentiated at the semantic level by differing conditions which must be imposed on the model systems used as interpretations for them. These model systems, and the conditions imposed upon them, are in turn described by means of a metalanguage which is essentially first-order quantificational logic. The power of this technique stems from the fact that for every object language formula of a system, there is a corresponding formula in the metalanguage which describes the conditions an interpretation must meet in order to satisfy the original formula. The conditions that the interpretations of a given system of logic must meet are reflected in this metalanguage as "antecedent assumptions," and these in turn correspond to cancellation rules for the object language. This correspondence is constructed in such a way that the metalinguistic counterpart of each theorem of the system will be a theorem of first-order logic. Snyder's primary interest is in showing how modal logic can be used, with the help of these techniques, to build a large variety of formal systems and to "tailor" such systems to meet a variety of analytical tasks. Simple modal systems are developed for the articulation of a number of modal concepts, in addition to the classic alethic ones. Examples are taken from temporal, deontic, and epistemic logic to show how specific interpretations of the meanings of the relevant operators lead to the incorporation of appropriate conditions in the formal systems used to articulate them. An entire chapter is devoted to a discussion of the paradoxes of material and strict implication, and to an attempt to articulate the notion of entailment through the development of formal systems which include a dyadic modal operator that is free of these paradoxes. The final chapter discusses such classical issues as proper names, reference, fictional entities, definite descriptions, and existence presuppositions. Appendices deal with such matters as the equivalence of the cancellation systems to more classical axiomatic-deduction systems, and the sketch of a proof of soundness and completeness for all the modal systems presented. While designed as a text, this volume should be of interest to both logicians and those working in metaphysics and language analysis, since the primary concern of the author is to develop techniques that will facilitate the usefulness of modal logic as a tool for philosophical analysis. The instructor's manual contains many suggestions derived from the author's experience in teaching this non-standard treatment of the subject.--K. T. (shrink)

The twenty-two essays collected for this book range widely in theme, style, and quality. The essays, a majority of which were previously unpublished, are arranged in three sections: 1) Early Essays, containing one particularly fine essay, "The Soul at Play," originally intended as part of Santayana's Soliloquies in England; 2) Later Essays, in which the title essay and "Friendship" are outstanding; and 3) Philosophical Essays, offering commentaries on Russell, Dewey, and James, on his own philosophy, and "On the False Steps (...) of Philosophy." The book's last article, "What is the Ego?", is an elaboration of his criticism of those "German Prophets" who return from self-contemplation "as greedy as children and as stubborn as Inquisitors." Santayana's manner of exposition often involves the elaboration of a single image or metaphor. When an image or metaphor is employed which can bear the weight of subtle distinctions, he is brilliant; but when the metaphor is too weak to encompass his thinking, then his writing becomes flowery and decadent. The essays, unfinished and fragmentary for the most part, are frequently little more than a single extended metaphor--sometimes over-extended. The fragmentary, possibly only experimental, ideas in these essays invite comparison with their use in his completed works. The book will be of special interest to someone already familiar with Santayana.--A. K. T. (shrink)

The editor has arranged forty-nine essays on and by Santayana into eight chapters representing major areas of Santayana's thought such as "Materialism and Idealism," "Essence, Substance, and Existence," "Art and Beauty." The essays supposedly speak to their chapter titles and to each other to create "the sense of dialogue"; with a few exceptions they were not written as deliberate conversation. This "dialogue" treats the reader to a fine display of the variety of minds and interests at work in philosophy and (...) illustrates the fact that one man's philosophical arena is rarely another man's. From J. H. Randall, Jr. to John Crowe Ransom, a recurring point of contention is Santayana's conception of Essences and their relationship to Matter. The range of interpretation on this issue goes from plaintive objections that "Essences don't do anything!" to appreciative acknowledgment that "Essences don't do anything!". Arguments over "isms" abound; realism, idealism, epiphenominalism are examined from many angles besides Santayana's. Santayana is highlighted nicely, arranged in this way beside his critics. His ability to locate the vital force behind an idea and to indicate where specific thrusts of thought will lead evinces his title of philosopher and master critic. This collection is not limited in appeal to Santayana aficionados.--A. K. T. (shrink)

Despite the title, some of the essays are devoted to matters which are not strictly epistemological. Both Malcolm and Stoutland are concerned with accounting for the connection between intention and the object of intention. Malcolm reviews Wittgenstein's thoughts on the subject while Stoutland gives an account of intentions in terms of teleology. With an eye toward the free will and skepticism controversies, White attempts an account of "What Might Have Been," distinguishing between existential and problematic possibilities. The remaining essays delve (...) into the topics of traditional epistemology. Oliver gives "A Sober Look at Solipsism" focussing attention on its 'causal' and 'privacy' postulates. Taking up the challenge of skepticism, Unger argues that "Our Knowledge of the Material World" not only is a reality, but is a function of our immediate experience. We can't help but believe such experiences, just as dogs must. The attempt is made by Pollock to map out "The Structure of Epistemic Justification" and he eschews a deductive model of explanation in favor of showing that logical reasons are but one kind of good reason--good reasons being the stuff of justification. Knox argues that "Do Appearances Exist?" deserves an affirmative answer as a consequence of the fact that we perceive objects, given his treatment of appearances as events. This is an interesting collection of essays, albeit for the non-subscriber, an expensive one.--K. T. (shrink)